Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230825 | 0.85 | HDAC3 (0.34) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL231623 | 0.85 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL232692 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL162659 | 0.79 | ALDH1A1 (0.35) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL230699 | 0.77 | PARG (0.32) | KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL230086 | 0.77 | GAA (0.38) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL230650 | 0.75 | LMNA (0.36) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL3226506 | 0.75 | ALDH1A1 (0.36) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL230842 | 0.74 | ALDH1A1 (0.35) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL17184104 | 0.73 | MEN1 (0.33) | KDM4EGAAMAPTL3MBTL1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | US | claimed |
| WO-2010005692-A2 | INSECTICIDAL CYCLIC CARBONYL AMIDINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-14 | — | — | WO | claimed |
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2010005692-A2 | INSECTICIDAL CYCLIC CARBONYL AMIDINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | DDT, PRMT9, PNISR | KDM4E 1810/4885GAA 2667/4885MAPT 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.