SCHEMBL230828

SCHEMBL230828

C=CC(=O)OCCn1c(=O)n(CCO)c(=O)n(CCOC(=O)C=C)c1=O

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 5/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 3/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 1/20 0.42
THRB P10828 2/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 2/20 0.32
NPSR1 Q6W5P4 2/20 0.31
POLB P06746 1/20 0.31
PLA2G4A P47712 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776295 1.00 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2730490 0.94 TSHR (0.49) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL42549 0.93 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9266437 0.91 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12993031 0.91 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17589483 0.90 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27900308 0.89 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL23964456 0.87 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15631086 0.87 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2730786 0.86 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293851-B Photo-curing resin composition and optical device prepared from same 长兴特殊材料(苏州)有限公司 2021-09-28 CN claimed
US-9822259-B2 Surface treatment composition DAIKIN INDUSTRIES, LTD. (JP) 2017-11-21 US claimed
US-20160304743-A1 SURFACE TREATMENT COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2016-10-20 US claimed
EP-1813972-B1 Alignment Film NIPPON KAYAKU KK (JP) 2012-10-10 EP claimed
US-7445820-B2 Optical films comprising a UV-curable alignment film and a liquid crystal compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 US claimed
US-7442420-B2 Retardation films comprising a UV-curable alignment film and a liquid crystal compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-10-28 US claimed
US-6916540-B2 Second layer formed under the first layercomprising a needle-like antimony-containing tin oxide to reduce static JSR CORPORATION (JP) 2005-07-12 US claimed
US-5919603-A Process for producing printed wiring board HITACHI, LTD. (JP) 1999-07-06 US claimed
EP-0869154-A1 COATING COMPOSITION FORMING WEAR-RESISTANT COAT AND ARTICLE COVERED WITH THE COAT MITSUBISHI RAYON CO., LTD. (JP) 1998-10-07 EP claimed
US-5449702-A Coating composition and process for producing abrasion-resistant synthetic resin molded articles MITSUBISHI RAYON CO., LTD. (JP) 1995-09-12 US claimed
US-5438751-A Using developer with a chlorine-free organic solvent HITACHI, LTD. (JP) 1995-08-08 US claimed
EP-0543393-B1 Coating composition MITSUBISHI RAYON CO (JP) 1995-07-19 EP claimed
US-5260361-A Acrylic ester-urethane crosslinked polymer MITSUBISHI RAYON CO., LTD. (JP) 1993-11-09 US claimed
EP-0543393-A1 Coating composition MITSUBISHI RAYON CO., LTD (JP) 1993-05-26 EP claimed
US-4943479-A RADIATION POLYMERIZABLE BINDER LAYER, ACRYLIC COMPOUND WITH TRIAZINE RING FUJI PHOTO FILM CO., LTD. (JP) 1990-07-24 US claimed
US-20260090252-A1 HARD COATING COMPOSITION AND ANTI-REFLECTION FILM INCLUDING A HARD COATING LAYER SAMSUNG DISPLAY CO LTD (KR) 2026-03-26 US disclosed
EP-3591443-B1 IMAGE DISPLAY DEVICE NIPPON KAYAKU KK (JP) 2024-07-17 EP disclosed
US-4943479-A RADIATION POLYMERIZABLE BINDER LAYER, ACRYLIC COMPOUND WITH TRIAZINE RING FUJI PHOTO FILM CO., LTD. (JP) 1990-07-24 US disclosed
EP-0298448-A2 Radiation-curable adhesive tape THE FURUKAWA ELECTRIC CO., LTD. (JP) 1989-01-11 EP disclosed
US-4664734-A RADIATION POLYMERIZATION FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090252-A1 HARD COATING COMPOSITION AND ANTI-REFLECTION FILM INCLUDING A HARD COATING LAYER ITGA1, ITGB1, RCC1 TSHR 2574/4885ALDH1A1 2496/4885TP53 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.