Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906344 | 0.84 | LPL (0.42) | LPLLIPGIDO1TDO2IRAK4 | |
| SCHEMBL23084786 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL21731218 | 0.69 | LPL (0.44) | LPLLIPGIRAK4ESR2CA1 | |
| SCHEMBL23084648 | 0.69 | ADRA2A (0.32) | — | |
| SCHEMBL21176822 | 0.68 | BACE1 (0.37) | LPLLIPGBACE1IDO1TDO2 | |
| SCHEMBL27007905 | 0.67 | BACE1 (0.30) | BACE1 | |
| SCHEMBL21392309 | 0.67 | LIPG (0.54) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL20206428 | 0.67 | LPL (0.42) | LPLLIPGIDO1TDO2IRAK4 | |
| SCHEMBL17673204 | 0.67 | LPL (0.40) | LPLLIPGBACE1IRAK4ESR2 | |
| SCHEMBL18239340 | 0.67 | IRAK4 (0.44) | LPLLIPGBACE1IRAK4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046183-A1 | METHODS OF TREATING EPILEPSY USING THE SAME | TREVENA, INC. (US) | 2021-03-11 | — | — | WO | disclosed |