Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776207 | 0.80 | L3MBTL1 (0.62) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL6996191 | 0.80 | HDAC3 (0.60) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL6646602 | 0.79 | CRBN (0.76) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL29995492 | 0.79 | SMYD3 (0.59) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL939611 | 0.79 | SMYD3 (0.59) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL27599042 | 0.77 | CRBN (0.54) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| Succinimide SCHEMBL9294241 | 0.77 | SMYD3 (0.58) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL9375237 | 0.77 | SIRT2 (0.61) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL2592775 | 0.77 | PKM (0.58) | SMYD3CRBNHDAC3HDAC4HDAC1 | |
| SCHEMBL5460664 | 0.77 | CRBN (0.53) | SMYD3CRBNHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046183-A1 | METHODS OF TREATING EPILEPSY USING THE SAME | TREVENA, INC. (US) | 2021-03-11 | — | — | WO | disclosed |