Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.86 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.86 |
| ▸ | ACHE | P22303 | 3/20 | 0.76 |
| ▸ | BACE1 | P56817 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.67 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | MGLL | Q99685 | 6/20 | 0.66 |
| ▸ | YAP1 | P46937 | 1/20 | 0.66 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553796 | 0.90 | PTPN1 (0.76) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL23086052 | 0.88 | MGLL (0.80) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL16332685 | 0.86 | YAP1 (0.71) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL1554428 | 0.84 | PTPN1 (0.67) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL17275229 | 0.83 | YAP1 (0.72) | PTPN1PTPN2LMNAPABPC1EIF4H | |
| SCHEMBL2831686 | 0.83 | EPHX2 (0.66) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL9309916 | 0.83 | ALDH1A1 (0.84) | PTPN1PTPN2ACHEBACE1LMNA | |
| SCHEMBL21926464 | 0.83 | RHOA (0.69) | PTPN1PTPN2LMNAALDH1A1 | |
| SCHEMBL23086098 | 0.80 | MGLL (1.00) | PTPN1PTPN2ALDH1A1MGLL | |
| SCHEMBL1673861 | 0.80 | MAPT (0.73) | PTPN1PTPN2ACHEMGLLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042911-A1 | MAGL INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 鲁南制药集团股份有限公司 | 2021-03-11 | — | — | WO | disclosed |