Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.84 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 4/20 | 0.64 |
| ▸ | BACE1 | P56817 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817987 | 0.86 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2EPHX2LMNAPOLB | |
| SCHEMBL2831686 | 0.84 | EPHX2 (0.66) | ALDH1A1SMN1; SMN2EPHX2PTPN2PTPN1 | |
| SCHEMBL2757942 | 0.84 | LMNA (0.85) | ALDH1A1SMN1; SMN2EPHX2PTPN2PTPN1 | |
| SCHEMBL10759312 | 0.84 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2EPHX2PTPN2PTPN1 | |
| SCHEMBL10197837 | 0.83 | NPC1 (0.69) | ALDH1A1SMN1; SMN2LMNAPOLBMGLL | |
| SCHEMBL23086155 | 0.83 | PTPN1 (0.86) | ALDH1A1EPHX2PTPN2PTPN1ACHE | |
| SCHEMBL12060563 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2EPHX2LMNAPOLB | |
| SCHEMBL3614803 | 0.82 | ACHE (0.70) | ALDH1A1SMN1; SMN2EPHX2PTPN2PTPN1 | |
| SCHEMBL1673861 | 0.82 | MAPT (0.73) | SMN1; SMN2EPHX2PTPN2PTPN1ACHE | |
| SCHEMBL2835506 | 0.81 | TSHR (0.68) | ALDH1A1SMN1; SMN2EPHX2PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298503-A | Cardiovascular | ADIR ET COMPAGNIE (FR) | 1994-03-29 | — | — | US | disclosed |