Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142129 | 0.79 | ALDH1A1 (0.31) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL23087141 | 0.74 | ANPEP (0.30) | — | |
| SCHEMBL2961477 | 0.71 | ALDH1A1 (0.32) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL28532420 | 0.70 | TAS1R3 (0.32) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL5421024 | 0.69 | ALDH1A1 (0.30) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL14994992 | 0.68 | — | — | |
| SCHEMBL4552495 | 0.68 | ALDH1A1 (0.36) | HRH3ALDH1A1POLBMAPTHTT | |
| SCHEMBL23087150 | 0.67 | ALDH1A1 (0.35) | HRH3ALDH1A1POLBMAPTHTT | |
| SCHEMBL6015185 | 0.67 | ALDH1A1 (0.33) | HRH3ALDH1A1POLBMAPTHTT | |
| SCHEMBL16834202 | 0.66 | ALDH1A1 (0.34) | HRH3ALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11291983-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2022-04-05 | — | — | US | claimed |
| US-20210077988-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | Apeiron Synthesis S. A. (PL) | 2021-03-18 | — | — | US | claimed |
| WO-2023158768-A1 | DUAL CATALYST SYSTEM FOR MASS ROMP AND CATIONIC POLYMERIZABLE COMPOSITIONS | PROMERUS, LLC (US) | 2023-08-24 | — | — | WO | disclosed |
| US-11554365-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2023-01-17 | — | — | US | disclosed |
| US-20220176362-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | Apeiron Synthesis S. A. (PL) | 2022-06-09 | — | — | US | disclosed |
| US-11291983-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2022-04-05 | — | — | US | disclosed |
| US-20210077988-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | Apeiron Synthesis S. A. (PL) | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11554365-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | RCOR1, NFE2L2, ARL1 | HRH3 1093/4885ALDH1A1 759/4885POLB 2081/4885 |
| US-20220176362-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | RCOR1, NFE2L2, ARL1 | HRH3 1093/4885ALDH1A1 759/4885POLB 2081/4885 |
| US-20210077988-A1 | ORGANORUTHENIUM CARBIDE COMPLEXES AS PRECATALYSTS FOR OLEFIN METATHESIS | RCOR1, OXER1, ARL1 | HRH3 1093/4885ALDH1A1 739/4885POLB 2064/4885 |
| US-11291983-B2 | Organoruthenium carbide complexes as precatalysts for olefin metathesis | RCOR1, OXER1, ARL1 | HRH3 1093/4885ALDH1A1 739/4885POLB 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.