SCHEMBL2961477

SCHEMBL2961477

Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)[PH](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.30
TAS1R1 Q7RTX1 2/20 0.30
TAS1R2 Q8TE23 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15135077 0.83 TAS1R3 (0.30) TAS1R3TAS1R1TAS1R2
SCHEMBL5421024 0.80 ALDH1A1 (0.30) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL31272969 0.79
SCHEMBL14994991 0.76
SCHEMBL26110875 0.74 CRHR1 (0.33)
SCHEMBL23087149 0.71 HRH3 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL5471894 0.69 ALDH1A1 (0.30) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL30142129 0.69 ALDH1A1 (0.31) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL23087150 0.68 ALDH1A1 (0.35) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL727932 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669330-B2 Olefin triblock polymers via ring-opening metathesis polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-03-11 US claimed
US-8283419-B2 Olefin functionalization by metathesis reaction EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-09 US claimed
US-20240140946-A1 N-1 BRANCHED CYCLOALKYL SUBSTITUTED IMIDAZO[4,5-c]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-05-02 US disclosed
US-11884662-B2 N-1 branched cycloalkyl substituted imidazo[4,5-c]quinoline compounds, compositions, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-30 US disclosed
WO-2024015412-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-01-18 WO disclosed
WO-2023127582-A1 POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION, AND ELECTRONIC COMPONENT 日本ゼオン株式会社 2023-07-06 WO disclosed
US-11565511-B2 Co-injection molded multilayer structure and method for producing same KURARAY CO., LTD. (JP) 2023-01-31 US disclosed
EP-3802536-B1 N-1 BRANCHED CYCLOALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2022-07-13 EP disclosed
US-11383497-B2 Co-injection-molded multilayer structure KURARAY CO., LTD. (JP) 2022-07-12 US disclosed
US-11332496-B2 Stapled and stitched polypeptides and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-05-17 US disclosed
EP-3428203-B1 HYDROCARBON POLYMERS WITH ALKOXYSILANE TERMINAL GROUP BOSTIK SA (FR) 2022-04-27 EP disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
US-20060211834-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2006-09-21 US disclosed
US-20060205901-A1 Crosslinkable resin composition and resin formed body produced therefrom ZEON CORPORATION (JP) 2006-09-14 US disclosed
US-20060154099-A1 Multilayer body and method for producing same ZEON CORPORATION (JP) 2006-07-13 US disclosed
US-20060148722-A1 Novel lincomycin derivatives possessing antibacterial activity VICURON PHARMACEUTICALS INC. (US) 2006-07-06 US disclosed
US-20050215488-A1 Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides VICURON PHARMACEUTICALS INC. 2005-09-29 US disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed
US-20050043248-A1 Novel lincomycin derivatives possessing antimicrobial activity VICURON PHARMACEUTICALS INC. 2005-02-24 US disclosed
WO-2001072421-A1 POLYMER SUPPORTED CATALYSTS FOR OLEFIN METATHESIS GLAXO GROUP LIMITED (GB) 2001-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884662-B2 N-1 branched cycloalkyl substituted imidazo[4,5-c]quinoline compounds, compositions, and methods IFNG, IFNAR1, CCL5 ALDH1A1 773/4885POLB 939/4885MAPT 4615/4885
US-20060148722-A1 Novel lincomycin derivatives possessing antibacterial activity LCLAT1, LAS1L, NRDC ALDH1A1 2927/4885POLB 2163/4885MAPT 4511/4885
US-20050215488-A1 Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides PAM, MLYCD, PPT1 ALDH1A1 2254/4885POLB 3052/4885MAPT 4240/4885
US-20050043248-A1 Novel lincomycin derivatives possessing antimicrobial activity LCLAT1, NRDC, LAS1L ALDH1A1 2991/4885POLB 2201/4885MAPT 4461/4885
US-11332496-B2 Stapled and stitched polypeptides and uses thereof VIP, NGLY1, IAPP ALDH1A1 4451/4885POLB 1366/4885MAPT 3000/4885
US-20240140946-A1 N-1 BRANCHED CYCLOALKYL SUBSTITUTED IMIDAZO[4,5-c]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS IFNG, IFNAR1, CCL5 ALDH1A1 1543/4885POLB 877/4885MAPT 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.