Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525105 | 1.00 | PTGS2 (0.36) | PTGS2PTGS1ESR1ESR2ADRA2C | |
| SCHEMBL30525104 | 0.86 | PTGS2 (0.34) | PTGS2PTGS1ESR1ESR2ADRA2C | |
| SCHEMBL23088744 | 0.86 | PTGS2 (0.34) | PTGS2PTGS1ESR1ESR2ADRA2C | |
| SCHEMBL27475455 | 0.77 | BRD4 (0.36) | — | |
| SCHEMBL23088743 | 0.74 | ADRA2C (0.32) | PTGS2ADRA2CHRH1HTR3APDE4D | |
| SCHEMBL30525101 | 0.74 | ADRA2C (0.32) | PTGS2ADRA2CHRH1HTR3APDE4D | |
| SCHEMBL23955974 | 0.72 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL21840766 | 0.72 | — | — | |
| SCHEMBL29960979 | 0.72 | — | — | |
| SCHEMBL28811814 | 0.71 | ESR2 (0.56) | PTGS2PTGS1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743431-B1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-04-16 | — | — | EP | disclosed |
| CN-111757887-B | 1, 2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2023-08-01 | — | — | CN | disclosed |
| US-11691998-B2 | 1,2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerisation | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-07-04 | — | — | US | disclosed |
| US-20230086874-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-03-23 | — | — | US | disclosed |
| US-20210079032-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-03-18 | — | — | US | disclosed |
| CN-111757887-A | 1, 2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-10-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210079032-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | MT-CO1, MT-CO2, INF2 | PTGS2 1901/4885PTGS1 2622/4885ESR1 695/4885 |
| US-20230086874-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | MT-CO1, MT-CO2, INF2 | PTGS2 1903/4885PTGS1 2610/4885ESR1 695/4885 |
| US-11691998-B2 | 1,2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerisation | MT-CO1, MT-CO2, INF2 | PTGS2 1903/4885PTGS1 2610/4885ESR1 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.