Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727047 | 0.84 | BCL2L1 (0.48) | ALDH1A1MAPTLMNAHSP90AA1BCL2L1 | |
| SCHEMBL229513 | 0.83 | BCL2L1 (0.63) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL728368 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNABCL2L1MCL1 | |
| SCHEMBL17549662 | 0.75 | MEN1 (0.47) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL728360 | 0.72 | KMT2A (0.55) | ALDH1A1NPSR1BCL2L1MCL1RAB9A | |
| SCHEMBL225008 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL11204474 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL17549634 | 0.70 | HSD17B10 (0.52) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL8536624 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL29333092 | 0.69 | RAB9A (0.61) | ALDH1A1MAPTLMNARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329149-B2 | Topical lightening composition and uses thereof | AVON PRODUCTS, INC. (US) | 2012-12-11 | — | — | US | claimed |
| EP-2521558-A1 | TOPICAL LIGHTENING COMPOSITION AND USES THEREOF | Avon Products, Inc. (US) | 2012-11-14 | — | — | EP | claimed |
| US-20120003168-A1 | Topical Lightening Composition and Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-01-05 | — | — | US | claimed |
| WO-2011082044-A1 | TOPICAL LIGHTENING COMPOSITION AND USES THEREOF | AVON PRODUCTS, INC. (US) | 2011-07-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003168-A1 | Topical Lightening Composition and Uses Thereof | TYR, AOC3, TH | ALDH1A1 129/4885MAPT 793/4885NPSR1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.