Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493902 | 0.83 | ADRB2 (0.48) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL25016648 | 0.83 | ADRB2 (0.48) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL9283159 | 0.79 | ALDH1A1 (0.42) | SLC6A2SLC6A3LMNAHPGDAOC3 | |
| SCHEMBL9229402 | 0.79 | ALDH1A1 (0.42) | SLC6A2SLC6A3LMNAHPGDAOC3 | |
| SCHEMBL10274563 | 0.78 | ADRB2 (0.48) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL11949354 | 0.77 | ADRB2 (0.62) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL10291752 | 0.76 | ESR1 (0.47) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL3715871 | 0.76 | SLC6A3 (0.47) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL18435278 | 0.75 | MEN1 (0.48) | ADRB2SLC6A2SLC6A3SLC6A4TSHR | |
| SCHEMBL27583456 | 0.75 | MEN1 (0.48) | ADRB2SLC6A2SLC6A3SLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10946000-B2 | Method for treating cancer with combination therapy | REDHILL BIOPHARMA LTD. (IL) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10946000-B2 | Method for treating cancer with combination therapy | TPMT, KRAS, SDHA | ADRB2 901/4885SLC6A2 201/4885SLC6A3 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.