Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274977 | 0.88 | AGER (0.47) | AGERMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11510612 | 0.84 | EGFR (0.53) | AGERMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7112667 | 0.82 | HIF1A (0.50) | KMT2AMAPTL3MBTL1CA2CA12 | |
| SCHEMBL2993410 | 0.81 | MAOA (0.46) | MEN1KMT2AMAPTRAB9AL3MBTL1 | |
| SCHEMBL1239791 | 0.78 | MAPT (0.56) | AGERMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL16320719 | 0.77 | RXFP1 (0.48) | AGERMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11511854 | 0.73 | MAPT (0.47) | MEN1KMT2AMAPTCA2CA12 | |
| SCHEMBL5272368 | 0.73 | BCHE (0.47) | AGERMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5272425 | 0.73 | MAOA (0.42) | MEN1KMT2AMAPTRAB9AL3MBTL1 | |
| SCHEMBL5268852 | 0.72 | HDAC4 (0.44) | MEN1KMT2AMAPTGAACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302492-B1 | HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS | UNION THERAPEUTICS AS (DK) | 2021-03-17 | — | — | EP | disclosed |