Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993410 | 0.91 | MAOA (0.46) | MAOAMAOBMAPTCA2CA1 | |
| SCHEMBL5272368 | 0.90 | BCHE (0.47) | MAPTCA2CA1CA12CA9 | |
| SCHEMBL5270890 | 0.88 | HIF1A (0.44) | MAOBMAPTCA2CA1CA12 | |
| SCHEMBL2981314 | 0.87 | MAOA (0.49) | MAOAMAOBMAPTHSD17B10HIF1A | |
| SCHEMBL5269253 | 0.87 | MAPT (0.42) | MAOBMAPTCA2CA1CA12 | |
| SCHEMBL5274977 | 0.87 | AGER (0.47) | MAPTCA2CA1CA12CA9 | |
| SCHEMBL5272301 | 0.87 | MAPT (0.57) | MAPTCA2CA1CA12CA9 | |
| SCHEMBL5270148 | 0.87 | ACHE (0.42) | MAOBMAPTCA2CA1CA12 | |
| SCHEMBL5271190 | 0.85 | MAPT (0.37) | MAPTCA2CA1CA12CA9 | |
| SCHEMBL5269215 | 0.83 | ARG1 (0.41) | MAPTCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | claimed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | claimed |
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | disclosed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | KRT18, COL2A1, COL1A1 | MAOA 1173/4885MAOB 1699/4885MAPT 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.