Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270890 | 0.87 | HIF1A (0.44) | HIF1AMAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL11510612 | 0.85 | EGFR (0.53) | HIF1AMAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL2993410 | 0.82 | MAOA (0.46) | HIF1AMAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL11511854 | 0.82 | MAPT (0.47) | HIF1AMAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL23095650 | 0.82 | AGER (0.55) | HIF1AMAPTALDH1A1ALOX12CYP1A2 | |
| SCHEMBL802584 | 0.78 | HIF1A (0.74) | HIF1AMAPTHPGDALDH1A1MAOB | |
| SCHEMBL11513189 | 0.78 | MAPT (0.60) | HIF1AMAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL30208389 | 0.78 | HIF1A (0.74) | HIF1AMAPTHPGDALDH1A1MAOB | |
| Diethanolamine SCHEMBL5272761 | 0.78 | HIF1A (0.38) | HIF1AMAPTHPGDALDH1A1ALOX12 | |
| SCHEMBL7117303 | 0.77 | KDM4E (0.54) | MAPTHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353636-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002094208-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G - CLAIROL, INC. (US) | 2002-11-28 | — | — | WO | disclosed |
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147193-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | HIF1A 1318/4885MAPT 3531/4885HPGD 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.