Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.41 |
| ▸ | DHODH | Q02127 | 7/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748172 | 0.83 | DGAT1 (0.36) | DGAT1PDE4DKDM4ELMNAHSD17B10 | |
| SCHEMBL1748065 | 0.77 | DGAT1 (0.41) | DGAT1KDM4EHSD17B10 | |
| SCHEMBL5983523 | 0.76 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL2635153 | 0.76 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL1748238 | 0.76 | DGAT1 (0.42) | DGAT1KDM4EHSD17B10 | |
| SCHEMBL14074138 | 0.75 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL2311893 | 0.75 | NPC1 (0.35) | DGAT1PDE4DHSD17B10 | |
| SCHEMBL1748122 | 0.75 | DGAT1 (0.50) | DGAT1KDM4ELMNA | |
| SCHEMBL1748077 | 0.74 | DGAT1 (0.55) | DGAT1DHODHABCB1 | |
| SCHEMBL1747931 | 0.74 | DGAT1 (0.55) | DGAT1DHODHABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013166-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2011-09-06 | — | — | US | disclosed |
| EP-1633722-B1 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2011-08-03 | — | — | EP | disclosed |