Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099650 | 0.87 | KMT2A (0.47) | KMT2AMEN1HTR2CSLC6A4KDM4E | |
| SCHEMBL23092683 | 0.81 | MEN1 (0.53) | KMT2AMEN1KDM4ERAB9ANPC1 | |
| SCHEMBL23099689 | 0.80 | KMT2A (0.51) | KMT2AMEN1KDM4ERAB9ANPC1 | |
| SCHEMBL23092558 | 0.79 | REN (0.43) | KMT2AMEN1HTR2CSLC6A4KDM4E | |
| SCHEMBL23092556 | 0.79 | REN (0.43) | KMT2AMEN1HTR2CSLC6A4KDM4E | |
| SCHEMBL19112868 | 0.78 | GAA (0.52) | KMT2AKDM4EPOLBMAPTHTT | |
| SCHEMBL23092452 | 0.77 | SLC6A4 (0.48) | KMT2AMEN1HTR2CSLC6A4KDM4E | |
| SCHEMBL17572297 | 0.77 | GAA (0.42) | KMT2AMEN1KDM4ERAB9ANPC1 | |
| SCHEMBL7499427 | 0.77 | ALDH1A1 (0.56) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL23099712 | 0.77 | MAPT (0.51) | KMT2AMEN1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050992-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |