Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112868 | 0.87 | GAA (0.52) | ALDH1A1L3MBTL1KMT2ALMNATDP1 | |
| SCHEMBL17572297 | 0.86 | GAA (0.42) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL24629451 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL29769183 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL24630015 | 0.79 | LMNA (0.46) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL30118756 | 0.78 | TRPV1 (0.41) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4113034 | 0.78 | AAK1 (0.44) | MEN1KMT2A | |
| SCHEMBL19675770 | 0.77 | NLRP3 (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL23976270 | 0.77 | KMT2A (0.57) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL23099686 | 0.77 | KMT2A (0.49) | MEN1KMT2ALMNASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |