Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17572297 | 0.87 | GAA (0.42) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL7499427 | 0.87 | ALDH1A1 (0.56) | POLBKMT2AATMLMNAALDH1A1 | |
| SCHEMBL30118756 | 0.79 | TRPV1 (0.41) | KMT2AKDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL4113034 | 0.79 | AAK1 (0.44) | KMT2A | |
| SCHEMBL19675770 | 0.79 | NLRP3 (0.50) | MAPTALDH1A1 | |
| SCHEMBL23976270 | 0.78 | KMT2A (0.57) | POLBKMT2AKDM4EMAPTLMNA | |
| SCHEMBL23099686 | 0.78 | KMT2A (0.49) | GAAPOLBKMT2AKDM4EATM | |
| SCHEMBL24634990 | 0.78 | NPC1 (0.45) | POLBKMT2AKDM4EMAPTLMNA | |
| SCHEMBL19675697 | 0.78 | ALDH1A1 (0.48) | POLBKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL24630257 | 0.77 | SORT1 (0.43) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190111-B1 | PYRAZOLO[3,4-C]PYRIDINE DERIVATIVES | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2020-05-06 | — | — | EP | disclosed |
| EP-3190111-A1 | PYRAZOLO[3,4-C]PYRIDINE DERIVATIVES | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2017-07-12 | — | — | EP | disclosed |