SCHEMBL2309969

SCHEMBL2309969

CCC(C)NC(=O)C(C)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.50
MMP2 P08253 1/20 0.50
MMP3 P08254 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.45
PKM P14618 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
EPHX1 P07099 1/20 0.41
ACACB O00763 1/20 0.41
RAB9A P51151 2/20 0.39
KDM4C Q9H3R0 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19699515 0.82 MMP1 (0.52) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL13912226 0.82 MMP1 (0.52) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL11527770 0.82 MMP1 (0.52) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL2313350 0.81 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL27118233 0.80 USP2 (0.52) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL9966033 0.80 MMP1 (0.50) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL1582575 0.80 CNR1 (0.40) ALDH1A1KMT2AMEN1ACACB
SCHEMBL2314196 0.80 MMP1 (0.46) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL8224748 0.80 MMP1 (0.50) MMP1MMP2MMP3SMN1; SMN2PKM
SCHEMBL12583433 0.78 MEN1 (0.38) MMP1MMP2MMP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2194778-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LTD (GB) 2017-01-18 EP claimed
US-20110190129-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LIMITED (GB) 2011-08-04 US claimed
EP-2194778-A2 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Syngenta Limited (GB) 2010-06-16 EP claimed
WO-2009027624-A2 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LIMITED (GB) 2009-03-05 WO claimed
CN-116590027-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal element JSR株式会社 2023-08-15 CN disclosed
CN-111849511-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal element JSR株式会社 2023-08-08 CN disclosed
CN-111849511-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2020-10-30 CN disclosed
CN-106047373-B Liquid crystal aligning agent JSR株式会社 2020-10-09 CN disclosed
EP-2194778-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LTD (GB) 2017-01-18 EP disclosed
EP-2001288-B1 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS SYNGENTA LTD (GB) 2015-06-24 EP disclosed
CN-101784186-B Improvements relating to organic compounds SYNGENTA LTD. (GB) 2014-10-08 CN disclosed
US-8420859-B2 Formulations SYNGENTA LIMITED (GB) 2013-04-16 US disclosed
EP-2194778-A2 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Syngenta Limited (GB) 2010-06-16 EP disclosed
WO-2009027624-A3 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LIMITED (GB) 2009-12-10 WO disclosed
US-20090227453-A1 FORUMLATIONS SYNGENTA LIMITED (GB) 2009-09-10 US disclosed
CN-101404879-A Process for producing lactamide compound, novel lactamide compound and preparation containing lactamide compound SYNGENTA LTD (GB) 2009-04-08 CN disclosed
WO-2009027624-A2 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LIMITED (GB) 2009-03-05 WO disclosed
WO-2009027624-A2 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS SYNGENTA LIMITED (GB) 2009-03-05 WO disclosed
EP-2001288-A2 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS Syngenta Limited (GB) 2008-12-17 EP disclosed
WO-2007107745-A2 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS SYNGENTA LIMITED (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190129-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS NR4A2, NR2C2, CYP4A22 MMP1 4684/4885MMP2 4139/4885MMP3 3936/4885
US-20090227453-A1 FORUMLATIONS CBR3, NR1H3, NR2C2 MMP1 4739/4885MMP2 4488/4885MMP3 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.