Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318399 | 0.85 | FLT3 (0.42) | FLT3MERTKGAS6GABRA1GABRA5 | |
| SCHEMBL23103351 | 0.83 | FLT3 (0.41) | FLT3MERTKGAS6PRMT5WDR77 | |
| SCHEMBL3318397 | 0.81 | FLT3 (0.42) | FLT3MERTKGAS6 | |
| SCHEMBL518379 | 0.77 | ALDH1A1 (0.44) | FLT3MERTKGAS6 | |
| SCHEMBL3537599 | 0.76 | SIGMAR1 (0.51) | ELANECXCR4 | |
| SCHEMBL14307263 | 0.76 | CXCR4 (0.53) | CHRM1CXCR4 | |
| SCHEMBL18291391 | 0.75 | PDE1B (0.47) | PRMT5WDR77GABRA1GABRA5CHRM1 | |
| SCHEMBL1126479 | 0.74 | GAA (0.46) | — | |
| SCHEMBL1126385 | 0.74 | NAMPT (0.46) | FLT3MERTKGAS6 | |
| SCHEMBL27833137 | 0.73 | FLT3 (0.39) | FLT3MERTKGAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |