Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.47 |
| ▸ | CDC25B | P30305 | 8/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311035 | 0.92 | NT5E (0.44) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL11102696 | 0.92 | NT5E (0.45) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL16633056 | 0.90 | LGALS3 (0.46) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL8654521 | 0.90 | HTR1A (0.46) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL17456127 | 0.90 | NT5E (0.48) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17456128 | 0.90 | NT5E (0.48) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL2312267 | 0.87 | LGALS3 (0.50) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL22677686 | 0.87 | SSTR1 (0.53) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL2309944 | 0.86 | NT5E (0.39) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL2309941 | 0.86 | NT5E (0.39) | NT5EHTR1APTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668143-B2 | Meningococcus serogroup X conjugate | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2020-06-02 | — | — | US | disclosed |
| US-10124051-B2 | Meningococcus serogroup X conjugate | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2018-11-13 | — | — | US | disclosed |
| US-10001488-B2 | Synthesis and use of isotopically-labelled glycans | Asocación Centro de Investigación Cooperativa en Biomaterials (ES) | 2018-06-19 | — | — | US | disclosed |
| EP-2981541-B1 | SYNTHESIS AND USE OF ISOTOPICALLY-LABELLED GLYCANS | ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOP EN BIOMATERIALES (ES) | 2017-09-13 | — | — | EP | disclosed |
| US-20160025742-A1 | SYNTHESIS AND USE OF ISOTOPICALLY-LABELLED GLYCANS | ASOCACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOMATERIALES (ES) | 2016-01-28 | — | — | US | disclosed |
| US-20150104479-A1 | MENINGOCOCCUS SEROGROUP X CONJUGATE | NOVARTIS AG (CH) | 2015-04-16 | — | — | US | disclosed |
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10668143-B2 | Meningococcus serogroup X conjugate | O60361, MLEC, PDHX | NT5E 1694/4885HTR1A 3761/4885PTPN1 1871/4885 |
| US-20160025742-A1 | SYNTHESIS AND USE OF ISOTOPICALLY-LABELLED GLYCANS | FUT6, FUT5, ST6GAL1 | NT5E 1127/4885HTR1A 4742/4885PTPN1 4659/4885 |
| US-10001488-B2 | Synthesis and use of isotopically-labelled glycans | FUT6, FUT5, ST6GAL1 | NT5E 1127/4885HTR1A 4742/4885PTPN1 4659/4885 |
| US-20150104479-A1 | MENINGOCOCCUS SEROGROUP X CONJUGATE | O60361, MLEC, PDHX | NT5E 1694/4885HTR1A 3761/4885PTPN1 1871/4885 |
| US-10124051-B2 | Meningococcus serogroup X conjugate | O60361, PDHX, MLEC | NT5E 1903/4885HTR1A 3856/4885PTPN1 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.