SCHEMBL23113017

SCHEMBL23113017

O=C(OCc1ccccc1)c1[nH]ccc1-c1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
POLB P06746 2/20 0.47
LMNA P02545 2/20 0.46
RAB9A P51151 6/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
EGLN1 Q9GZT9 1/20 0.43
JMJD6 Q6NYC1 1/20 0.42
MMP2 P08253 2/20 0.42
MMP9 P14780 2/20 0.42
MMP12 P39900 2/20 0.42
NPC1 O15118 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26111532 0.84 LMNA (0.50) KMT2APOLBLMNARAB9ATSHR
SCHEMBL1477084 0.79 PRKCI (0.47) KMT2APOLBLMNARAB9AL3MBTL1
SCHEMBL26119478 0.75 PRKCI (0.46) POLBLMNARAB9ANPC1KDM4E
SCHEMBL29020260 0.74 TDP1 (0.53) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL14837183 0.74 ALDH1A1 (0.61) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL23112876 0.74 TDP1 (0.53) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL13505598 0.74 KMT2A (0.53) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL31556128 0.74 RAB9A (0.55) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL2911925 0.72 RAB9A (0.43) KMT2ATDP1SLC6A2SLC6A3POLB
SCHEMBL23113067 0.72 TDP1 (0.51) KMT2ATDP1SLC6A2SLC6A3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307515-A Antibacterial compounds 英菲克斯治疗有限公司 2024-07-09 CN disclosed
US-11845725-B2 Antibacterial compounds Infex Therapeutics Limited (GB) 2023-12-19 US disclosed
EP-3793990-B1 ANTIBACTERIAL COMPOUNDS INFEX THERAPEUTICS LTD (GB) 2023-07-19 EP disclosed
US-20230060011-A1 ANTIBACTERIAL COMPOUNDS Infex Therapeutics Limited (GB) 2023-02-23 US disclosed
US-11459296-B2 Antibacterial compounds Infex Therapeutics Limited (GB) 2022-10-04 US disclosed
US-20210230115-A1 Antibacterial Compounds Infex Therapeutics Limited (GB) 2021-07-29 US disclosed
EP-3793990-A1 ANTIBACTERIAL COMPOUNDS Infex Therapeutics Limited (GB) 2021-03-24 EP disclosed
CN-112449638-A Antibacterial compounds 英菲克斯治疗有限公司 2021-03-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060011-A1 ANTIBACTERIAL COMPOUNDS GAA, MGAM, NQO1 KMT2A 2035/4885TDP1 4465/4885SLC6A2 3841/4885
US-20210230115-A1 Antibacterial Compounds GAA, MGAM, NQO1 KMT2A 2035/4885TDP1 4465/4885SLC6A2 3841/4885
US-11459296-B2 Antibacterial compounds GAA, MGAM, NQO1 KMT2A 2035/4885TDP1 4465/4885SLC6A2 3841/4885
US-11845725-B2 Antibacterial compounds GAA, MGAM, NQO1 KMT2A 2035/4885TDP1 4465/4885SLC6A2 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.