SCHEMBL1477084

SCHEMBL1477084

O=C(O)c1[nH]ccc1-c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.47
PIN1 Q13526 1/20 0.46
KDM4E B2RXH2 5/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM6B O15054 1/20 0.46
KDM4A O75164 1/20 0.46
KDM5C P41229 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
KDM3A Q9Y4C1 1/20 0.46
LMNA P02545 3/20 0.43
P4HTM Q9NXG6 2/20 0.43
NAPRT Q6XQN6 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26119478 0.85 PRKCI (0.46) PRKCIPIN1KDM4EKDM4CKDM6B
SCHEMBL23113017 0.79 KMT2A (0.48) KDM4ELMNAL3MBTL1POLBKMT2A
SCHEMBL26111532 0.78 LMNA (0.50) KDM4ELMNAPOLBKMT2ANPC1
SCHEMBL5508637 0.76 PIN1 (0.43) PRKCIPIN1KDM4EKDM4CKDM6B
SCHEMBL29852117 0.75 TGFBR1 (0.54) PIN1KDM4EKDM4CKDM6BKDM4A
SCHEMBL23294714 0.75 TGFBR1 (0.54) PIN1KDM4EKDM4CKDM6BKDM4A
SCHEMBL30457761 0.75 PRKCI (0.53) PRKCIKDM4ELMNAP4HTML3MBTL1
SCHEMBL11886372 0.75 PRKCI (0.53) PRKCIPIN1KDM4ELMNAP4HTM
SCHEMBL404747 0.74 PRKCI (0.56) PRKCIKDM4ELMNAP4HTML3MBTL1
SCHEMBL1330600 0.74 MAPT (0.48) PIN1KDM4ECYP1A2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9796743-B2 Bidentate heteroleptic square planar complexes of (pyridyl)azolates UNIVERSITY OF NORTH TEXAS (US) 2017-10-24 US claimed
WO-2015154958-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING A LIGHT-EMITTING DEVICE OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2015-10-15 WO claimed
WO-2015084906-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS (US) 2015-06-11 WO claimed
US-20150155504-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS 2015-06-04 US claimed
WO-2019048415-A1 LED, USE OF AN LED, METHOD FOR OPERATING AN LED, AND METHOD FOR PRODUCING AN LED OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2019-03-14 WO disclosed
US-9796743-B2 Bidentate heteroleptic square planar complexes of (pyridyl)azolates UNIVERSITY OF NORTH TEXAS (US) 2017-10-24 US disclosed
US-9796743-B2 Bidentate heteroleptic square planar complexes of (pyridyl)azolates UNIVERSITY OF NORTH TEXAS (US) 2017-10-24 US disclosed
US-9796743-B2 Bidentate heteroleptic square planar complexes of (pyridyl)azolates UNIVERSITY OF NORTH TEXAS (US) 2017-10-24 US disclosed
US-9772270-B2 Devices and methods for recording information on a subject's body ELWHA LLC (US) 2017-09-26 US disclosed
WO-2015154958-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING A LIGHT-EMITTING DEVICE OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2015-10-15 WO disclosed
WO-2015084906-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS (US) 2015-06-11 WO disclosed
WO-2015084906-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS (US) 2015-06-11 WO disclosed
US-20150155504-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS 2015-06-04 US disclosed
US-20150155504-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES UNIVERSITY OF NORTH TEXAS 2015-06-04 US disclosed
US-20130046182-A1 Devices and Methods for Recording Information on a Subject's Body Elwha LLC, a limited liability company of the State of Delaware 2013-02-21 US disclosed
US-20130046227-A1 Devices and Methods for Recording Information on a Subject's Body Elwha LLC, a limited liability company of the State of Delaware 2013-02-21 US disclosed
US-7915414-B2 Blue-emitting organometallic complexes and their application Chi, Yun (TW) 2011-03-29 US disclosed
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application Chi, Yun (TW) 2008-05-29 US disclosed
CN-100335477-C Pyrazolecarboxamide insecticides DU PONT (US) 2007-09-05 CN disclosed
CN-1659160-A Pyrazolecarboxamide insecticides DU PONT (US) 2005-08-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155504-A1 BIDENTATE HETEROLEPTIC SQUARE PLANAR COMPLEXES OF (PYRIDYL)AZOLATES OCIAD2, ICOSLG, OCIAD1 PRKCI 1404/4885PIN1 25/4885KDM4E 1566/4885
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application CYBA, IK, CRY1 PRKCI 2621/4885PIN1 405/4885KDM4E 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.