Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115954 | 0.82 | KDM4E (0.33) | KDM4EGAARAB9AHTTLMNA | |
| SCHEMBL23115887 | 0.75 | KDM4E (0.37) | KDM4EGAARAB9ALMNAMEN1 | |
| SCHEMBL23116106 | 0.74 | LMNA (0.39) | KDM4ERAB9ALMNAPOLBTDP1 | |
| SCHEMBL23115696 | 0.73 | S1PR1 (0.42) | KDM4EGAARAB9ALMNAPOLB | |
| SCHEMBL23115592 | 0.72 | KDM4E (0.42) | KDM4EHTTPOLBALDH1A1 | |
| SCHEMBL23115820 | 0.72 | SMN1; SMN2 (0.40) | KDM4EGAARAB9ALMNAPOLB | |
| SCHEMBL23115716 | 0.69 | QPCTL (0.41) | GAARAB9AHTTMEN1KMT2A | |
| SCHEMBL22121357 | 0.68 | KDM4E (0.49) | KDM4EHTTLMNAPOLBHDAC8 | |
| SCHEMBL26928056 | 0.65 | ALDH1A1 (0.34) | KDM4ERAB9ALMNAPOLBMEN1 | |
| SCHEMBL31459755 | 0.63 | ASAH1 (0.40) | KDM4EGAAHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2025-05-13 | — | — | US | disclosed |
| EP-4034534-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114728946-A | Polyheterocyclic modulators of STING (stimulator of interferon genes) | 辉瑞公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | GPR119 1307/4885KDM4E 3785/4885GAA 473/4885 |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | GPR119 1307/4885KDM4E 3785/4885GAA 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.