Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22501030 | 1.00 | TSHR (0.39) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1471988 | 1.00 | TSHR (0.39) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL23494267 | 0.83 | GABRR1 (0.37) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL11352108 | 0.83 | KISS1R (0.35) | LMNATDP1RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL11352111 | 0.83 | KISS1R (0.35) | LMNATDP1RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL15353 | 0.81 | — | — | |
| SCHEMBL15352 | 0.81 | — | — | |
| SCHEMBL12973059 | 0.81 | — | — | |
| SCHEMBL23494364 | 0.81 | TSHR (0.38) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL23494092 | 0.81 | BLM (0.38) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479549-B | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2023-09-12 | — | — | CN | claimed |
| US-11597895-B2 | Aromatic substance mixtures containing 8,8-dimethyl-6,10-dioxaspiro[4,5]decane | SYMRISE AG (DE) | 2023-03-07 | — | — | US | claimed |
| EP-3723709-B1 | PERFUME MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | claimed |
| US-20210087500-A1 | AROMATIC SUBSTANCE MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-25 | — | — | US | claimed |
| CN-111479549-B | Aromatic substance mixture containing 8, 8-dimethyl-6, 10-dioxaspiro [4.5] decane | 西姆莱斯有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3723709-B1 | PERFUME MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | SYMRISE AG (DE) | 2021-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597895-B2 | Aromatic substance mixtures containing 8,8-dimethyl-6,10-dioxaspiro[4,5]decane | TAS2R8, TRPM8, DHPS | TSHR 1736/4885GABRR1 2815/4885GABRR2 2986/4885 |
| US-20210087500-A1 | AROMATIC SUBSTANCE MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE | TAS2R8, TRPM8, DHPS | TSHR 1736/4885GABRR1 2815/4885GABRR2 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.