Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729528 | 0.93 | EPHX2 (0.42) | HRH1CCR3ALDH1A1HPGDGRIN2D | |
| SCHEMBL23116376 | 0.91 | KDM4E (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2EPHX2 | |
| SCHEMBL22729452 | 0.90 | ADRB2 (0.42) | ALDH1A1HPGDSMN1; SMN2FPR2PROKR1 | |
| SCHEMBL22729684 | 0.90 | SPR (0.44) | HRH1CCR3ALDH1A1MAPTHPGD | |
| SCHEMBL29839387 | 0.89 | HRH1 (0.51) | HRH1CCR3FPR2PROKR1KCNH2 | |
| SCHEMBL23116424 | 0.89 | HRH1 (0.51) | HRH1CCR3FPR2PROKR1KCNH2 | |
| SCHEMBL22755115 | 0.89 | TRPA1 (0.48) | HRH1CCR3ALDH1A1MAPTHPGD | |
| SCHEMBL29839346 | 0.89 | TRPA1 (0.48) | HRH1CCR3ALDH1A1MAPTHPGD | |
| SCHEMBL22729777 | 0.88 | MMP13 (0.44) | FPR2PROKR1EPHX2MGLLKCNH2 | |
| SCHEMBL22729640 | 0.88 | CYP46A1 (0.41) | ALDH1A1MAPTHPGDNPSR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | HRH1 2169/4885CCR3 4608/4885ALDH1A1 2626/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | HRH1 2145/4885CCR3 4592/4885ALDH1A1 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.