SCHEMBL23120252

SCHEMBL23120252

CCS(=O)(=O)c1cc(C2(C#N)CC2)cnc1-c1nc2cc(S(=O)(=NC3CC3)C(F)(F)F)ccc2n1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 14/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ KCNH2 Q12809 1/20 0.33
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ CA12 O43570 2/20 0.31
▸ CA9 Q16790 2/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ KIT P10721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29748644 0.90 LMNA (0.36) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL23120298 0.90 LMNA (0.36) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL30092782 0.90 LMNA (0.35) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL23120234 0.90 LMNA (0.35) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL23120246 0.89 — —
SCHEMBL29748745 0.86 LMNA (0.38) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL23120278 0.86 LMNA (0.38) CNR2LMNAHTTSMN1; SMN2KCNH2
SCHEMBL29748678 0.83 UTRN (0.34) —
SCHEMBL23121378 0.83 UTRN (0.34) —
SCHEMBL28938657 0.81 MET (0.35) CNR2LMNAHTTSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503461-B2 Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents SYNGENTA CROP PROTECTION AG (CH) 2025-12-23 — — US claimed
EP-4031544-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-02-28 — — EP claimed
US-20220372026-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-11-24 — — US claimed
EP-4031544-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2022-07-27 — — EP claimed
WO-2021053110-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 — — WO claimed
US-12503461-B2 Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents SYNGENTA CROP PROTECTION AG (CH) 2025-12-23 — — US disclosed
EP-4031544-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-02-28 — — EP disclosed
EP-4031544-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-02-28 — — EP disclosed
US-20220372026-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-11-24 — — US disclosed
EP-4031544-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2022-07-27 — — EP disclosed
WO-2021053110-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 — — WO disclosed
WO-2021053110-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372026-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR AND SULFOXIMINE CONTAINING SUBSTITUENTS SQOR, TST, DDT CNR2 808/4885LMNA 4854/4885HTT 1549/4885
US-12503461-B2 Pesticidally active heterocyclic derivatives with sulfur and sulfoximine containing substituents SQOR, TST, DDT CNR2 808/4885LMNA 4854/4885HTT 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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