Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747536 | 0.87 | CPB1 (0.45) | GSTO1PTPRBFFAR2ALDH1A1TSHR | |
| SCHEMBL21757533 | 0.80 | CCNK (0.53) | USP30UCHL1FFAR2CCNKCDK9 | |
| SCHEMBL21757581 | 0.78 | GSTO1 (0.35) | USP30UCHL1GSTO1PTPRBFFAR2 | |
| SCHEMBL23125489 | 0.73 | CCNK (0.44) | USP30UCHL1GSTO1PTPRBFFAR2 | |
| SCHEMBL21757604 | 0.71 | CCNK (0.42) | USP30UCHL1GSTO1PTPRBFFAR2 | |
| SCHEMBL21747538 | 0.70 | EIF4E (0.46) | CYP3A4ROCK1CCNKCDK9 | |
| SCHEMBL104784 | 0.69 | GPR119 (0.33) | KMT2ASMN1; SMN2HPGDCDK9MAPK1 | |
| SCHEMBL1192313 | 0.68 | CNR2 (0.35) | TSHRKMT2ACDK9MAPK1 | |
| SCHEMBL448401 | 0.67 | CYP3A4 (0.57) | ALDH1A1MEN1KMT2ACYP3A4ROCK1 | |
| SCHEMBL21747534 | 0.67 | CCNK (0.59) | FFAR2CPB1CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10952999-B2 | Inhibitor of cyclin-dependent kinase CDK9 | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2021-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10952999-B2 | Inhibitor of cyclin-dependent kinase CDK9 | CDK9, CDK19, CDK1 | USP30 1848/4885UCHL1 3034/4885GSTO1 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.