Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863190 | 0.90 | PARP1 (0.47) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL7348724 | 0.86 | PARP1 (0.41) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL11615870 | 0.84 | KDM4E (0.42) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL4975651 | 0.84 | PARP1 (0.42) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL10416488 | 0.84 | PARP1 (0.42) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL709378 | 0.81 | GSK3B (0.43) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL6347009 | 0.81 | PARP1 (0.40) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL28160075 | 0.80 | MAOA (0.46) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL10879460 | 0.80 | PARP1 (0.39) | PARP1GSK3BKDM4EALDH1A1GAA | |
| SCHEMBL170914 | 0.80 | GABRA1 (0.49) | PARP1GSK3BKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402448-B | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2023-03-17 | — | — | CN | claimed |
| CN-113402448-A | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2021-09-17 | — | — | CN | claimed |
| US-6657081-B1 | Extraction of actinides and lanthanides from aqueous solutions | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2003-12-02 | — | — | US | claimed |
| CN-113402448-B | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-113402448-B | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-113402448-A | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2021-09-17 | — | — | CN | disclosed |
| CN-113402448-A | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2021-09-17 | — | — | CN | disclosed |
| EP-3796900-A1 | TRITERPENE AMINE DERIVATIVES | DFH Therapeutics (US) | 2021-03-31 | — | — | EP | disclosed |
| US-20130190407-A1 | CALCIUM RECEPTOR-ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-7989451-B2 | Tricyclic 1,2,4-triazine oxides and compositions for therapeutic use in cancer treatments | AUCKLAND UNISERVICES LIMITED (NZ) | 2011-08-02 | — | — | US | disclosed |
| EP-1866292-B1 | TRICYCLIC 1,2,4-TRIAZINE OXIDES AND COMPOSITIONS THEREFROM FOR THERAPEUTIC USE IN CANCER TREATMENTS | AUCKLAND UNISERVICES LTD (NZ) | 2010-12-15 | — | — | EP | disclosed |
| US-5294715-A | Acridine-intercalator based hypoxia selective cytotoxins | UNIVERSITY OF PITTSBURGH (US) | 1994-03-15 | — | — | US | disclosed |
| US-5264576-A | Antiserotonin agents, antidepressants and obsessive-compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993004373-A1 | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1993000906-A1 | MUSCARINIC ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4613695-A | ANTITUMOR | AKTIEBOLAGET LEO (SE) | 1986-09-23 | — | — | US | disclosed |
| EP-0194046-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4568685-A | THROMBOXANE SYNTHETASE ENZYME INHIBITORS, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-02-04 | — | — | US | disclosed |
| US-4038412-A | ANTI-VIRAL AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190407-A1 | CALCIUM RECEPTOR-ACTIVE MOLECULES | CASR, CALCR, ORAI1 | PARP1 2764/4885GSK3B 4383/4885KDM4E 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.