Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316255 | 0.85 | KMT2A (0.55) | KDM4EPOLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL4135386 | 0.83 | MAOA (0.50) | MAOAMAOBKDM4EPOLBALDH1A1 | |
| SCHEMBL2312989 | 0.81 | MTNR1A (0.50) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL19810785 | 0.81 | PTGER4 (0.53) | MTNR1AMTNR1BAKR1C3ABCB1SMN1; SMN2 | |
| SCHEMBL2317908 | 0.80 | KDM4E (0.46) | KDM4EPOLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL13877023 | 0.79 | MAOA (0.61) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4674534 | 0.79 | ABCB1 (0.59) | ABCB1HTR1ADRD2APEX1 | |
| SCHEMBL7568923 | 0.77 | SMN1; SMN2 (0.51) | KDM4EPOLBSMN1; SMN2CYP19A1 | |
| SCHEMBL8889562 | 0.77 | NPC1 (0.52) | MAOAKDM4EALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL7125179 | 0.76 | MTNR1A (0.58) | KDM4EPOLBMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349964-B1 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C A I R BIOSCIENCES GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| EP-2349964-B1 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C A I R BIOSCIENCES GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
| EP-2349964-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | c-a-i-r biosciences GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-2206534-A1 | Dibenzocycloheptanone derivatives und pharmaceutical agents containing these compounds | c-a-i-r biosciences GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| WO-2010040843-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010040843-A2 | DIBENZOCYCLOHEPTANONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | IL1B, NFKBIA, IL1R1 | MAOA 2492/4885MAOB 1589/4885KDM4E 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.