Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347744 | 1.00 | ALOX5 (0.36) | ALOX5PRKCZRAB9AADORA2BCYP1A2 | |
| SCHEMBL17347832 | 0.90 | ALOX5 (0.36) | ALOX5PRKCZRAB9AADORA2BMAPT | |
| SCHEMBL23837292 | 0.90 | POLB (0.32) | RAB9APOLBALDH1A1 | |
| SCHEMBL23130166 | 0.90 | ALOX5 (0.36) | ALOX5PRKCZRAB9AADORA2BMAPT | |
| SCHEMBL19663625 | 0.89 | PRKCZ (0.35) | PRKCZRAB9AADORA2BMAPTALDH1A1 | |
| SCHEMBL23130177 | 0.89 | ALOX5 (0.37) | ALOX5PRKCZRAB9AADORA2BMAPT | |
| SCHEMBL17347806 | 0.89 | ALOX5 (0.37) | ALOX5PRKCZRAB9AADORA2BMAPT | |
| SCHEMBL23129955 | 0.88 | CA12 (0.42) | PRKCZMAPTALDH1A1CA12CA1 | |
| SCHEMBL17347776 | 0.88 | CA12 (0.42) | PRKCZMAPTALDH1A1CA12CA1 | |
| SCHEMBL17347748 | 0.87 | HTT (0.35) | ALOX5PRKCZRAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |