Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | GRM6 | O15303 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347832 | 1.00 | ALOX5 (0.36) | ALOX5GRM6POLBRAB9AADORA2B | |
| SCHEMBL17347806 | 0.92 | ALOX5 (0.37) | ALOX5POLBRAB9AADORA2BMEN1 | |
| SCHEMBL23130177 | 0.92 | ALOX5 (0.37) | ALOX5POLBRAB9AADORA2BMEN1 | |
| SCHEMBL17347744 | 0.90 | ALOX5 (0.36) | ALOX5GRM6POLBRAB9AADORA2B | |
| SCHEMBL23129690 | 0.90 | ALOX5 (0.36) | ALOX5GRM6POLBRAB9AADORA2B | |
| SCHEMBL19663664 | 0.89 | ALDH1A1 (0.34) | RAB9AADORA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL23129709 | 0.88 | CA12 (0.41) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17347783 | 0.88 | CA12 (0.41) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17347789 | 0.88 | MTNR1A (0.33) | MEN1KMT2AALDH1A1MAPK1CA12 | |
| SCHEMBL23130023 | 0.88 | MTNR1A (0.33) | MEN1KMT2AALDH1A1MAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |