Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAT | P04040 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347774 | 1.00 | CAT (0.33) | CATKDM4EALDH1A1HSD17B10DPP4 | |
| SCHEMBL17347789 | 0.87 | MTNR1A (0.33) | CATKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL23130023 | 0.87 | MTNR1A (0.33) | CATKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL17347939 | 0.87 | — | — | |
| SCHEMBL23130021 | 0.86 | OPRD1 (0.35) | CATCA1CA2CA12CA7 | |
| SCHEMBL23130017 | 0.85 | CAT (0.48) | CATCA1CA2CA12CA7 | |
| SCHEMBL17347763 | 0.85 | CAT (0.48) | CATCA1CA2CA12CA7 | |
| SCHEMBL17347656 | 0.85 | MTNR1A (0.36) | CATALDH1A1CA1CA2CA12 | |
| SCHEMBL17347744 | 0.85 | ALOX5 (0.36) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL23129690 | 0.85 | ALOX5 (0.36) | ALDH1A1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |