Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23130245 | 1.00 | DRD2 (0.32) | DRD2GRM5MTNR1AMTNR1BTSHR | |
| SCHEMBL17347812 | 0.92 | MTNR1A (0.31) | DRD2GRM5MTNR1AMTNR1B | |
| SCHEMBL17337282 | 0.91 | TDP1 (0.36) | DRD2GRM5MTNR1AMTNR1BTSHR | |
| SCHEMBL17337279 | 0.91 | TDP1 (0.36) | DRD2GRM5MTNR1AMTNR1BTSHR | |
| SCHEMBL17337247 | 0.90 | PRKCB (0.32) | — | |
| SCHEMBL17337244 | 0.90 | PRKCB (0.32) | — | |
| SCHEMBL23130266 | 0.90 | MEN1 (0.32) | — | |
| SCHEMBL17347807 | 0.90 | MEN1 (0.32) | — | |
| SCHEMBL17347682 | 0.88 | TRPA1 (0.34) | DRD2GRM5MTNR1AMTNR1B | |
| SCHEMBL23130265 | 0.88 | TSHR (0.39) | DRD2GRM5MTNR1AMTNR1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |