Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347820 | 1.00 | OPRK1 (0.34) | OPRK1TSHRALOX5SMN1; SMN2MAPT | |
| SCHEMBL23130190 | 0.91 | ALDH1A1 (0.32) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17347784 | 0.91 | ALDH1A1 (0.32) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17347686 | 0.89 | CA12 (0.33) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23130283 | 0.89 | CA12 (0.33) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23129649 | 0.86 | — | — | |
| SCHEMBL17347841 | 0.86 | — | — | |
| SCHEMBL17347744 | 0.86 | ALOX5 (0.36) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23129690 | 0.86 | ALOX5 (0.36) | OPRK1ALOX5SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17347833 | 0.85 | CAT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |