Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31506926 | 0.93 | KDM4E (0.54) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL23133247 | 0.82 | MEN1 (0.52) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL21184262 | 0.82 | MAPT (0.54) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL31045646 | 0.75 | CYP3A4 (0.56) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL1518339 | 0.74 | MAPT (0.50) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL31065716 | 0.72 | MEN1 (1.00) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL11879018 | 0.71 | ATAD2 (0.52) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL4961428 | 0.70 | LMNA (0.54) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL668116 | 0.70 | CYP3A4 (0.51) | KDM4EMEN1KMT2AMAPTTAAR1 | |
| SCHEMBL356483 | 0.69 | TYMP (0.49) | KDM4EATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055849-A1 | HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2021-03-25 | — | — | WO | disclosed |