SCHEMBL668116

SCHEMBL668116

C=CCNc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.51
▸ MAPT P10636 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.50
▸ DPYD Q12882 2/20 0.47
▸ LMNA P02545 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ POLB P06746 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.38
▸ GAA P10253 1/20 0.38
▸ ATAD2 Q6PL18 1/20 0.38
▸ CYP19A1 P11511 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ HBB P68871 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31045646 0.83 CYP3A4 (0.56) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL21184262 0.76 MAPT (0.54) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL30608338 0.73 MAPT (0.59) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL1518339 0.71 MAPT (0.50) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL4961428 0.71 LMNA (0.54) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL23133109 0.70 KDM4E (0.56) MAPTMEN1KMT2AKDM4ETAAR1
SCHEMBL2552963 0.70 CYP3A4 (0.57) CYP3A4MAPTMEN1KMT2AKDM4E
SCHEMBL30464745 0.69 CYP3A4 (0.49) CYP3A4DPYD
SCHEMBL30464746 0.69 CYP3A4 (0.49) CYP3A4DPYD
SCHEMBL17803639 0.69 CA12 (0.37) CYP3A4KMT2AKDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1005 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 — — CN claimed
CN-118076741-A Modified mRNA, modified non-coding RNA and uses thereof 布罗德研究所股份有限公司 2024-05-24 — — CN claimed
WO-2013071079-A1 LIN28/LET-7 CRYSTAL STRUCTURES, PURIFICATION PROTOCOLS, AND MOLECULAR PROBES SUITABLE FOR SCREENING ASSAYS AND THERAPEUTICS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-05-16 — — WO claimed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof — 2026-05-26 — — CN disclosed
CN-122095091-A DsRNA for inhibiting LPA gene expression and application thereof — 2026-05-26 — — CN disclosed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 — — US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 — — WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 — — US disclosed
WO-2026098737-A1 NUCLEIC ACID CONJUGATE AND PHARMACEUTICAL COMPOSITION FOR LIPID DELIVERY, AND USE THEREOF 苏州时安生物技术有限公司 2026-05-15 — — WO disclosed
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 — — CN disclosed
WO-2010011895-A1 ENHANCEMENT OF SIRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND ALNYLAM PHARMACEUTICALS, INC. (US) 2010-01-28 — — WO disclosed
WO-2009155504-A2 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-23 — — WO disclosed
WO-2009149239-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-10 — — WO disclosed
WO-2009126933-A2 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2009-10-15 — — WO disclosed
WO-2009120878-A2 NON-NATURAL RIBONUCLEOTIDES, AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. (US) 2009-10-01 — — WO disclosed
WO-1995006751-A9 METHODS FOR ISOLATION OF MOST ABUNDANT OLIGONUCLEOTIDES FROM COMPLEX MIXTURES — 1995-04-20 — — WO disclosed
WO-1995006751-A1 METHODS FOR ISOLATION OF MOST ABUNDANT OLIGONUCLEOTIDES FROM COMPLEX MIXTURES PHARMAGENICS, INC. (US) 1995-03-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD CYP3A4 3396/4885MAPT 4097/4885MEN1 4354/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 CYP3A4 3105/4885MAPT 1032/4885MEN1 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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