Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12641734 | 0.75 | ALDH1A1 (0.38) | PNMTDPP4BPTFKAT2BNCF1 | |
| Hydrochloric Acid SCHEMBL29904871 | 0.73 | BPTF (0.37) | PNMTDPP4BPTFKAT2BNCF1 | |
| SCHEMBL24850316 | 0.71 | — | — | |
| SCHEMBL13153503 | 0.71 | FAAH (0.35) | — | |
| SCHEMBL1106459 | 0.71 | PTGS2 (0.42) | PNMTDPP4BPTFKAT2BPTGS2 | |
| SCHEMBL1695159 | 0.68 | DDR1 (0.34) | PNMTBPTFKAT2B | |
| SCHEMBL23121361 | 0.68 | NPC1 (0.45) | — | |
| SCHEMBL15799041 | 0.68 | BRD4 (0.50) | — | |
| SCHEMBL23134010 | 0.66 | CRBN (0.54) | — | |
| SCHEMBL4754442 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |