Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22503913 | 0.82 | CYP3A4 (0.50) | — | |
| SCHEMBL17289569 | 0.81 | APLNR (0.41) | ALDH1A1ALOX15CYP1B1 | |
| SCHEMBL14679718 | 0.75 | — | — | |
| SCHEMBL77709 | 0.74 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL14294799 | 0.74 | — | — | |
| SCHEMBL7130891 | 0.70 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL9358004 | 0.68 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL27509660 | 0.67 | — | — | |
| SCHEMBL2313556 | 0.67 | LMNA (0.36) | ALDH1A1 | |
| SCHEMBL3891088 | 0.67 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627452-B1 | UV-absorbing polyurethanes and polyesters | CIBA GEIGY AG (CH) | 1998-12-09 | — | — | EP | claimed |
| EP-0507727-B1 | Glass coating with improved adhesion and weather resistance | CIBA GEIGY AG (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | claimed |
| EP-0362145-B1 | Crosslinked siloxane-urethane polymer contact lens | CIBA GEIGY AG (CH) | 1996-01-03 | — | — | EP | claimed |
| US-5459222-A | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY CORPORATION | 1995-10-17 | — | — | US | claimed |
| US-5426204-A | Trialkoxysilane with urea, urethane, sulfide or amide linkages | CIBA-GEIGY CORPORATION (US) | 1995-06-20 | — | — | US | claimed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |
| US-5372889-A | Glass coating with improved adhesion and weather resistance | CIBA-GEIGY CORPORATION (US) | 1994-12-13 | — | — | US | claimed |
| EP-0627452-A1 | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY AG (CH) | 1994-12-07 | — | — | EP | claimed |
| US-5334681-A | High oxygen permeability; resiliency, flexibility; wettability; biocompatibility | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | claimed |
| US-5266715-A | Covalent bonding of a siloxane-urea compound to form crosslinked copolymer | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| EP-0507727-A2 | Glass coating with improved adhesion and weather resistance | CIBA-GEIGY AG (CH) | 1992-10-07 | — | — | EP | claimed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | claimed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | claimed |
| US-4983702-A | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| EP-0362145-A2 | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | claimed |
| US-8778476-B2 | High speed DVDs | BAYER MATERIALSCIENCE AG (DE) | 2014-07-15 | — | — | US | disclosed |
| EP-0109355-B1 | SILICON-CONTAINING POLYMERS HAVING AN INCREASED OXYGEN PERMEABILITY | CIBA-GEIGY AG (CH) | 1986-08-13 | — | — | EP | disclosed |
| EP-0109355-A1 | Silicon-containing polymers having an increased oxygen permeability | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |