Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313561 | 0.81 | ALDH1A1 (0.38) | ALOX15CYP1B1ALDH1A1 | |
| SCHEMBL19673987 | 0.76 | APLNR (0.43) | APLNR | |
| SCHEMBL29265192 | 0.63 | APLNR (0.59) | APLNR | |
| SCHEMBL289935 | 0.62 | — | — | |
| SCHEMBL6953544 | 0.59 | PLAU (0.46) | APLNR | |
| SCHEMBL29433031 | 0.59 | PLAU (0.46) | APLNR | |
| SCHEMBL6081194 | 0.58 | — | — | |
| SCHEMBL710256 | 0.58 | — | — | |
| SCHEMBL9839353 | 0.57 | — | — | |
| SCHEMBL11543558 | 0.57 | DRD2 (0.42) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344613-A1 | POLYTHIOUREA COMPOSITIONS AND METHODS OF USE | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344613-A1 | POLYTHIOUREA COMPOSITIONS AND METHODS OF USE | PNMT, SRM, PUF60 | APLNR 1356/4885ALOX15 4253/4885CYP1B1 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.