Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 8/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344306 | 0.85 | HTR2A (0.53) | LMNAALDH1A1GAACYP1A2POLB | |
| SCHEMBL10067358 | 0.78 | KMT2A (0.46) | LMNAGAACYP1A2HTR6MEN1 | |
| SCHEMBL2345067 | 0.77 | HTR6 (0.40) | LMNAALDH1A1CYP1A2HPGDCYP3A4 | |
| SCHEMBL5472616 | 0.74 | MEN1 (0.59) | LMNAALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5472611 | 0.74 | MEN1 (0.59) | LMNAALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL12432042 | 0.73 | LMNA (0.41) | LMNAALDH1A1GAACYP1A2SMN1; SMN2 | |
| SCHEMBL1792194 | 0.72 | ALDH1A1 (0.62) | LMNAALDH1A1GAACYP1A2POLB | |
| SCHEMBL30534146 | 0.72 | ALDH1A1 (0.62) | LMNAALDH1A1GAACYP1A2POLB | |
| SCHEMBL14519065 | 0.70 | ALDH1A1 (0.60) | LMNAALDH1A1GAACYP1A2POLB | |
| SCHEMBL8998884 | 0.70 | ALDH1A1 (0.60) | LMNAALDH1A1CYP1A2POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039724-B1 | Indole-derived styryl dye comprising an alkylene linker, dye composition comprising this dye, process for lightening keratin materials using this dye | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-2039724-B1 | Indole-derived styryl dye comprising an alkylene linker, dye composition comprising this dye, process for lightening keratin materials using this dye | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-7744658-B2 | Indole-derived styryl dye comprising an alkylene linker, a dye composition comprising this dye, and a process for lightening keratin materials using this dye | L'OREAL S.A. (FR) | 2010-06-29 | — | — | US | disclosed |
| US-7744658-B2 | Indole-derived styryl dye comprising an alkylene linker, a dye composition comprising this dye, and a process for lightening keratin materials using this dye | L'OREAL S.A. (FR) | 2010-06-29 | — | — | US | disclosed |
| US-7744658-B2 | Indole-derived styryl dye comprising an alkylene linker, a dye composition comprising this dye, and a process for lightening keratin materials using this dye | L'OREAL S.A. (FR) | 2010-06-29 | — | — | US | disclosed |
| US-20090089939-A1 | INDOLE-DERIVED STYRYL DYE COMPRISING AN ALKYLENE LINKER, A DYE COMPOSITION COMPRISING THIS DYE, AND A PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL S.A. (FR) | 2009-04-09 | — | — | US | disclosed |
| US-20090089939-A1 | INDOLE-DERIVED STYRYL DYE COMPRISING AN ALKYLENE LINKER, A DYE COMPOSITION COMPRISING THIS DYE, AND A PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL S.A. (FR) | 2009-04-09 | — | — | US | disclosed |
| US-20090089939-A1 | INDOLE-DERIVED STYRYL DYE COMPRISING AN ALKYLENE LINKER, A DYE COMPOSITION COMPRISING THIS DYE, AND A PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL S.A. (FR) | 2009-04-09 | — | — | US | disclosed |
| EP-2039724-A1 | Indole-derived styryl dye comprising an alkylene linker, dye composition comprising this dye, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-03-25 | — | — | EP | disclosed |
| EP-2039724-A1 | Indole-derived styryl dye comprising an alkylene linker, dye composition comprising this dye, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090089939-A1 | INDOLE-DERIVED STYRYL DYE COMPRISING AN ALKYLENE LINKER, A DYE COMPOSITION COMPRISING THIS DYE, AND A PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | KRT18, VIM, CYBA | LMNA 660/4885ALDH1A1 258/4885GAA 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.