Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232020 | 0.88 | HSD11B1 (0.47) | HSD11B1LMNASMN1; SMN2ATMALDH1A1 | |
| SCHEMBL232475 | 0.83 | THRB (0.43) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL10065063 | 0.79 | HSD11B1 (0.49) | HSD11B1LMNASMN1; SMN2ATMALDH1A1 | |
| SCHEMBL2753761 | 0.78 | POLB (0.40) | HSD11B1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2753822 | 0.77 | FFAR1 (0.42) | MAPTMEN1KMT2AHTT | |
| SCHEMBL2753631 | 0.74 | FFAR1 (0.51) | HSD11B1 | |
| SCHEMBL3106053 | 0.73 | HSD11B1 (0.44) | HSD11B1LMNAMAPTMEN1KMT2A | |
| SCHEMBL15468352 | 0.73 | KMT2A (0.47) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL230611 | 0.71 | THRB (0.48) | ALDH1A1KDM4EGAAL3MBTL1HTT | |
| SCHEMBL18597731 | 0.71 | MAPT (0.45) | LMNAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590931-B1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENT | SANOFI SA (FR) | 2014-04-30 | — | — | EP | disclosed |
| US-8648038-B2 | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments | SANOFI (FR) | 2014-02-11 | — | — | US | disclosed |
| US-8648038-B2 | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments | SANOFI (FR) | 2014-02-11 | — | — | US | disclosed |
| US-8648038-B2 | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments | SANOFI (FR) | 2014-02-11 | — | — | US | disclosed |
| EP-2590931-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | GPR119, DPP9, DPP7 | HSD11B1 2645/4885LMNA 2973/4885MAPT 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.