Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229257 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ATMLMNASMN1; SMN2POLB | |
| SCHEMBL48352 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ATMLMNASMN1; SMN2POLB | |
| SCHEMBL69354 | 0.97 | — | — | |
| SCHEMBL224023 | 0.92 | — | — | |
| SCHEMBL24693081 | 0.87 | CA2 (0.50) | ALDH1A1ATMLMNASMN1; SMN2POLB | |
| SCHEMBL11742016 | 0.87 | L3MBTL1 (0.52) | ALDH1A1ATMLMNASMN1; SMN2POLB | |
| SCHEMBL9279972 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2POLBHTT | |
| SCHEMBL11844730 | 0.86 | — | — | |
| SCHEMBL8978116 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2POLBHTT | |
| SCHEMBL22481550 | 0.82 | HPGD (0.62) | ALDH1A1ATMLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874601-A | 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof | 山东大学 | 2025-04-25 | — | — | CN | claimed |
| EP-3938345-B1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250263375-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2025-08-21 | — | — | US | disclosed |
| CN-119874601-A | 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof | 山东大学 | 2025-04-25 | — | — | CN | disclosed |
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2023-06-22 | — | — | US | disclosed |
| US-11603355-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-03-14 | — | — | US | disclosed |
| CN-112110845-B | Synthesis method of bazedoxifene and analogues thereof | 中国科学院福建物质结构研究所 | 2022-06-10 | — | — | CN | disclosed |
| US-10981887-B2 | Benzothiophene estrogen receptor modulators | G1 THERAPEUTICS, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10968179-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210061763-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2021-03-04 | — | — | US | disclosed |
| US-4116677-A | N-alkyl-alpha-(substituted phenoxy) alkylamides and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4110105-A | Aromatic N-substituted halo-substituted-2-pyrrolidinones and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4099954-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |
| US-4090864-A | Herbicidal acetamidothiomethyl ureas | STAUFFER CHEMICAL COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4069038-A | Acyclic and alicyclic N-substituted halo-2-pyrrolidinones and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-4068079-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-4056524-A | BIS-SUBSTITUTED SUCCINAMIDES AND THEIR UTILITY AS HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
| US-4018813-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-3998808-A | INSECTICIDES, FUNGICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3997526-A | HERBICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981887-B2 | Benzothiophene estrogen receptor modulators | ESR1, GPER1, ESR2 | ALDH1A1 1156/4885ATM 3633/4885LMNA 4716/4885 |
| US-20250263375-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV2, TRPV5 | ALDH1A1 2736/4885ATM 4775/4885LMNA 2685/4885 |
| US-11603355-B2 | Charged ion channel blockers and methods for use | TRPV1, TRPV2, TRPV5 | ALDH1A1 2736/4885ATM 4775/4885LMNA 2685/4885 |
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | TRPV1, TRPV2, TRPV5 | ALDH1A1 2736/4885ATM 4775/4885LMNA 2685/4885 |
| US-10968179-B2 | Charged ion channel blockers and methods for use | TRPV1, TRPV2, TRPV5 | ALDH1A1 2736/4885ATM 4775/4885LMNA 2685/4885 |
| US-20210061763-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | TRPV1, TRPV2, TRPV5 | ALDH1A1 2736/4885ATM 4775/4885LMNA 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.