Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | ACSL5 | Q9ULC5 | 1/20 | 0.39 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302074 | 0.83 | KDM4E (0.60) | GABRA5NAMPTKDM4ECNR2HDAC1 | |
| SCHEMBL20788418 | 0.82 | L3MBTL1 (0.57) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17796689 | 0.82 | GABRA5 (0.46) | GABRA5NAMPTKDM4EADORA2ACYP2C9 | |
| SCHEMBL20804091 | 0.79 | GABRA5 (0.44) | GABRA5NAMPTKDM4EADORA2AACSS2 | |
| SCHEMBL28773428 | 0.78 | POLB (0.50) | GABRA5KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17298875 | 0.78 | GABRA5 (0.44) | GABRA5NAMPTKDM4EADORA2ACYP2C9 | |
| SCHEMBL27960102 | 0.75 | BAZ2B (0.56) | SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL17499897 | 0.74 | THRB (0.64) | RAB9ACYP2C9NPC1SMN1; SMN2HDAC1 | |
| SCHEMBL12301890 | 0.74 | NPC1 (0.57) | NAMPTKDM4ERAB9ACYP2C9MAPK14 | |
| SCHEMBL20788451 | 0.72 | OGG1 (0.53) | NAMPTRAB9ANPC1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | claimed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | disclosed |