SCHEMBL231482

SCHEMBL231482

CC1(C(=O)Cl)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9661569 0.81
SCHEMBL9593948 0.80 SMN1; SMN2 (0.32)
SCHEMBL1136246 0.77
SCHEMBL9312275 0.77 PKM (0.31)
SCHEMBL248540 0.74
SCHEMBL31487839 0.74
SCHEMBL28019553 0.74 HPGD (0.35)
SCHEMBL9577996 0.74
SCHEMBL11819217 0.72
SCHEMBL9577974 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5146001-A PREPARATION OF BENZYL KETONES AND AN OXIRANE BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 US claimed
US-20250380697-A1 ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2025-12-18 US disclosed
US-9359362-B2 Triazolo and tetrazolo pyrimidine derivatives as HNE inhibitors for treating COPD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-06-07 US disclosed
US-20140038988-A1 TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-06 US disclosed
US-8569314-B2 Triazolo and tetrazolo pyrimidine derivatives as HNE inhibitors for treating COPD BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-10-29 US disclosed
US-20120004203-A1 TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2012-01-05 US disclosed
US-5288883-A Haloalkyl, benzyl or cycloalkylphenyl chemical intermediates BAYER AKTIENGESELLSCHAFT (DE) 1994-02-22 US disclosed
US-5264632-A Fungicide intermediate BAYER AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed
US-5216006-A FUNGICIDAL AZOLYL-PROPANOL DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1993-06-01 US disclosed
US-5208388-A Chemical intermediates for heterocyclic fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
US-5194636-A Preparation of benzyl ketones and an oxirane BAYER AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
US-5146001-A PREPARATION OF BENZYL KETONES AND AN OXIRANE BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 US disclosed
US-5097050-A Intermediates for synthesis of fungicidal hydroxyalkinyl-azoles BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
US-5095147-A Intermediates for fungicides BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
US-5025030-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-06-18 US disclosed
US-3954730-A ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed