SCHEMBL231491

SCHEMBL231491

CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSK P43235 13/20 0.56
ALDH1A1 P00352 1/20 0.45
CTSL P07711 3/20 0.41
CTSB P07858 3/20 0.41
CTSH P09668 2/20 0.41
CTSS P25774 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
BIRC2 Q13490 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4292353 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL18328801 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783726 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783728 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL15756119 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL258985 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8387889 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8972183 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8695376 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL9234715 0.93 CTSK (0.52) CTSKALDH1A1CTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP claimed
US-20250262268-A1 Methods and Compositions for Inhibiting Viral Infection NEW YORK UNIVERSITY 2025-08-21 US claimed
WO-2024153744-A1 AUTOPHAGY ACTIVATORS FOR THE TREATMENT OF RHABDOMYOLYSIS Institut National de la Santé et de la Recherche Médicale (FR) 2024-07-25 WO claimed
WO-2024150130-A2 NECROSIS INHIBITOR LINKGEVITY LIMITED (GB) 2024-07-18 WO claimed
WO-2024118561-A2 DYSREGULATION OF NEUROPROTEASOMES BY APOE ISOFORMS DRIVES ENDOGENOUS TAU AGGREGATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-06-06 WO claimed
EP-4313144-A1 COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME Angiex, Inc. (US) 2024-02-07 EP claimed
WO-2024018245-A1 USE OF CALPAIN INHIBITORS FOR THE TREATMENT OF THE DIABETIC KIDNEY DISEASE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2024-01-25 WO claimed
CN-117355333-A Combination comprising anti-TM 4SF1 antibody and immunotherapeutic agent and method of use thereof 安吉克公司 2024-01-05 CN claimed
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2023-09-21 US claimed
CN-217763217-U Road lighting and environmental monitoring integrated device 河北润衡环境治理有限公司 2022-11-08 CN claimed
WO-2000007619-A1 ALTERATION OF THE CELL CYCLE IN VIVO, AND PARTICULARLY FOR INDUCING APOPTOSIS OF TUMOR CELLS ALFACELL CORPORATION (US) 2000-02-17 WO claimed
WO-1999045974-A1 PROTEASE INHIBITORS IN ABSORBENT ARTICLES THE PROCTER & GAMBLE COMPANY (US) 1999-09-16 WO claimed
US-5942494-A Stimulation of gene expression and synthesis of heat shock protein 72/73 (HSP 70) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-08-24 US claimed
EP-0724429-B1 COMPOSITION AND METHOD FOR DELIVERY OF DRUGS ADVANCED RES & TECH INST (US) 1999-07-07 EP claimed
WO-1999025830-A1 TRANSCRIPTIONALLY REGULATED G PROTEIN-COUPLED RECEPTOR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-05-27 WO claimed
EP-0724429-A1 COMPOSITION AND METHOD FOR DELIVERY OF DRUGS INDIANA UNIVERSITY FOUNDATION (US) 1996-08-07 EP claimed
EP-0652290-A1 Method for regulation of NF-kB YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1995-05-10 EP claimed
US-5171217-A Injecting drug carried on microparticles of biocompatible biodegradable polymer into vessel wall under directed pressure INDIANA UNIVERSITY FOUNDATION (US) 1992-12-15 US claimed
WO-1992015282-A2 COMPOSITION AND METHOD FOR DELIVERY OF DRUGS INDIANA UNIVERSITY FOUNDATION (US) 1992-09-17 WO claimed
WO-1992013549-A1 INHIBITION OF CELL PROLIFERATION BY HYDROPHOBIC PEPTIDES RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-08-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME TM9SF4, TM9SF2, TM9SF3 CTSK 1456/4885ALDH1A1 2644/4885CTSL 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.