Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099586 | 0.88 | PDK2 (0.38) | ALDH1A1ALOX15PDK2NOTUMHSD17B10 | |
| SCHEMBL30537674 | 0.88 | PDK2 (0.38) | ALDH1A1ALOX15PDK2NOTUMKDM4E | |
| SCHEMBL28723246 | 0.88 | PDK2 (0.38) | ALDH1A1ALOX15PDK2NOTUMKDM4E | |
| SCHEMBL9221863 | 0.86 | PDK2 (0.37) | ALDH1A1ALOX15PDK2NOTUMHSD17B10 | |
| SCHEMBL9220858 | 0.85 | PDK2 (0.36) | ALDH1A1ALOX15PDK2NOTUMHSD17B10 | |
| SCHEMBL9455620 | 0.80 | PDK2 (0.33) | PDK2NOTUMHSD17B10CDC25ACDC25B | |
| SCHEMBL9455626 | 0.79 | CA12 (0.37) | PDK2CA12CA1CA4CA6 | |
| SCHEMBL23149793 | 0.76 | PDK2 (0.36) | ALDH1A1PDK2KDM4EMAPTMAOB | |
| SCHEMBL9220689 | 0.76 | ALOX5 (0.35) | ALDH1A1ALOX15PDK2NOTUMHSD17B10 | |
| SCHEMBL9215677 | 0.74 | KMT2A (0.34) | ALDH1A1ALOX15PDK2NOTUMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384092-B2 | Dianhydride compound having rigid alicyclic fluorine-containing structure, and preparation method and use thereof | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-12 | — | — | US | claimed |
| US-20210094965-A1 | DIANHYDRIDE COMPOUND HAVING RIGID ALICYCLIC FLUORINE-CONTAINING STRUCTURE, AND PREPARATION METHOD AND USE THEREOF | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-04-01 | — | — | US | claimed |
| US-11384092-B2 | Dianhydride compound having rigid alicyclic fluorine-containing structure, and preparation method and use thereof | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-12 | — | — | US | disclosed |
| US-20210094965-A1 | DIANHYDRIDE COMPOUND HAVING RIGID ALICYCLIC FLUORINE-CONTAINING STRUCTURE, AND PREPARATION METHOD AND USE THEREOF | HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384092-B2 | Dianhydride compound having rigid alicyclic fluorine-containing structure, and preparation method and use thereof | CA3, MLLT3, TET3 | ALDH1A1 357/4885ALOX15 2203/4885PDK2 3508/4885 |
| US-20210094965-A1 | DIANHYDRIDE COMPOUND HAVING RIGID ALICYCLIC FLUORINE-CONTAINING STRUCTURE, AND PREPARATION METHOD AND USE THEREOF | CA3, MLLT3, TET3 | ALDH1A1 357/4885ALOX15 2203/4885PDK2 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.