Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071586 | 0.91 | IDO1 (0.55) | IDO1SLC6A4HTR2CHTR2BCHRNB2 | |
| Trifluoroacetic Acid SCHEMBL23152297 | 0.90 | IDO1 (0.47) | IDO1SLC6A4HTR2CHTR2BLIPG | |
| Trifluoroacetic Acid SCHEMBL23150549 | 0.84 | MGLL (0.49) | SLC6A4HTR2CHTR2BFFAR4MRGPRX4 | |
| Trifluoroacetic Acid SCHEMBL25325427 | 0.82 | SLC6A4 (0.45) | SLC6A4HTR2CHTR2BKMT2AFFAR4 | |
| Trifluoroacetic Acid SCHEMBL23091803 | 0.81 | NAAA (0.43) | IDO1SLC6A4HTR2CHTR2BLIPG | |
| SCHEMBL21984758 | 0.80 | IDO1 (0.55) | IDO1SLC6A4HTR2CHTR2BCHRNB2 | |
| SCHEMBL3124123 | 0.78 | IDO1 (0.52) | IDO1SLC6A4HTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL23149361 | 0.77 | IDO1 (0.43) | IDO1SLC6A4CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL30490311 | 0.76 | IDO1 (0.42) | IDO1SLC6A4LIPGLPLLIPC | |
| Trifluoroacetic Acid SCHEMBL23149170 | 0.76 | LPL (0.46) | SLC6A4HTR2CHTR2BLIPGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP4B1 | IDO1 1568/4885SLC6A4 4134/4885HTR2C 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.