Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484519 | 0.92 | DRD4 (0.40) | DRD4KDM4EMAPK1SCN9ALMNA | |
| SCHEMBL17797569 | 0.87 | LMNA (0.34) | DRD4EPHX2KDM4ELMNAKMT2A | |
| SCHEMBL20573229 | 0.85 | EPHX2 (0.38) | EPHX2LMNAKMT2APSEN1PSEN2 | |
| SCHEMBL3389669 | 0.85 | EPHX2 (0.40) | EPHX2LMNAKMT2ANCOA3PSEN1 | |
| SCHEMBL963562 | 0.84 | NPC1 (0.42) | DRD4EPHX2MAPK1PIK3CGLMNA | |
| SCHEMBL5802385 | 0.84 | EPHX2 (0.42) | EPHX2KMT2ANCOA3PSEN1PSEN2 | |
| SCHEMBL5725028 | 0.81 | ALDH1A1 (0.33) | EPHX2KDM4ELMNAKMT2AGAA | |
| SCHEMBL965090 | 0.80 | KDM4E (0.46) | KDM4EMAPK1KMT2ANPC1RAB9A | |
| SCHEMBL2484468 | 0.80 | KDM4E (0.46) | KDM4EMAPK1KMT2ANPC1RAB9A | |
| SCHEMBL20184269 | 0.79 | ALDH1A1 (0.44) | KDM4EMAPK1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057190-A1 | QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海阳帆医药科技有限公司 | 2021-04-01 | — | — | WO | disclosed |