Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566164 | 0.88 | AOC2 (0.36) | — | |
| SCHEMBL28566163 | 0.88 | AOC2 (0.36) | — | |
| SCHEMBL11606604 | 0.84 | — | — | |
| SCHEMBL23152007 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL15687144 | 0.80 | ALDH1A1 (0.34) | — | |
| SCHEMBL21437566 | 0.78 | — | — | |
| SCHEMBL8538497 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL4940256 | 0.76 | KCNH2 (0.34) | CNR2CNR1KCNH2 | |
| SCHEMBL21410746 | 0.75 | TDP1 (0.36) | — | |
| SCHEMBL28645664 | 0.75 | MAOA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284604-A | Fused heterocycles as RIPK1 inhibitors | 比西切姆有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117561257-A | Tricyclic compounds as anticancer agents | 晶锐医药(苏州)有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4281451-A1 | TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS | Jingrui Biopharma Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| CN-117098760-A | Compositions and methods for treating KIT and PDGFRA mediated diseases | 缆图药品公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-108558871-B | Tricyclic compounds as anticancer agents | 百时美施贵宝公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-107614501-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| EP-2125792-A1 | PURINE DERIVATIVES AS IMMUNOMODULATORS | Smithkline Beecham Corporation (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008101867-A1 | PURINE DERIVATIVES AS IMMUNOMODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |